Sciweavers

BMCBI
2011
14 years 8 months ago
A fast and accurate method to detect allelic genomic imbalances underlying mosaic rearrangements using SNP array data
Background: Mosaicism for copy number and copy neutral chromosomal rearrangements has been recently identified as a relatively common source of genetic variation in the normal pop...
Juan R. González, Benjamin Rodriguez-Santia...
BMCBI
2011
14 years 8 months ago
Efficient alignment of pyrosequencing reads for re-sequencing applications
Background: Over the past few years, new massively parallel DNA sequencing technologies have emerged. These platforms generate massive amounts of data per run, greatly reducing th...
Francisco Fernandes, Paulo G. S. da Fonseca, Lu&ia...
BMCBI
2011
14 years 8 months ago
Learning sparse models for a dynamic Bayesian network classifier of protein secondary structure
Background: Protein secondary structure prediction provides insight into protein function and is a valuable preliminary step for predicting the 3D structure of a protein. Dynamic ...
Zafer Aydin, Ajit Singh, Jeff Bilmes, William Staf...
BMCBI
2011
14 years 8 months ago
FIND: A new software tool and development platform for enhanced multicolor flow analysis
Background: Flow Cytometry is a process by which cells, and other microscopic particles, can be identified, counted, and sorted mechanically through the use of hydrodynamic pressu...
Shareef Dabdoub, William C. Ray, Sheryl S. Justice
BMCBI
2011
14 years 8 months ago
Proteinortho: Detection of (Co-)Orthologs in Large-Scale Analysis
Background: Orthology analysis is an important part of data analysis in many areas of bioinformatics such as comparative genomics and molecular phylogenetics. The ever-increasing ...
Marcus Lechner, Sven Findeiß, Lydia Steiner,...
BMCBI
2011
14 years 8 months ago
A user-friendly web portal for T-Coffee on supercomputers
Background: Parallel T-Coffee (PTC) was the first parallel implementation of the T-Coffee multiple sequence alignment tool. It is based on MPI and RMA mechanisms. Its purpose is t...
Josep Rius Torrento, Fernando Cores, Francesc Sols...
BMCBI
2011
14 years 8 months ago
The Proteogenomic Mapping Tool
Background: High-throughput mass spectrometry (MS) proteomics data is increasingly being used to complement traditional structural genome annotation methods. To keep pace with the...
William S. Sanders, Nan Wang, Susan M. Bridges, Br...
BMCBI
2011
14 years 8 months ago
BICEPP: an example-based statistical text mining method for predicting the binary characteristics of drugs
Background: The identification of drug characteristics is a clinically important task, but it requires much expert knowledge and consumes substantial resources. We have developed ...
Frank P. Y. Lin, Stephen Anthony, Thomas M. Polase...
BMCBI
2011
14 years 8 months ago
ShoRAH: estimating the genetic diversity of a mixed sample from next-generation sequencing data
Background: With next-generation sequencing technologies, experiments that were considered prohibitive only a few years ago are now possible. However, while these technologies hav...
Osvaldo Zagordi, Arnab Bhattacharya, Nicholas Erik...