BMCBI
2004
13 years 4 months ago
2004
Background: DopaNet http://www.dopanet.org is a Systems Biology initiative that aims to investigate precisely and quantitatively all the aspects of neurotransmission in a specific...
BMCBI
2004
13 years 4 months ago
2004
The hit criterion is a key component of heuristic local alignment algorithms. It specifies a class of patterns assumed to witness a potential similarity, and this choice is decisi...
BMCBI
2004
13 years 4 months ago
2004
Background: Research involving expressed sequence tags (ESTs) is intricately coupled to the existence of large, well-annotated sequence repositories. Comparatively complete and sa...
BMCBI
2004
13 years 4 months ago
2004
Background: Certain protein families are highly conserved across distantly related organisms and belong to large and functionally diverse superfamilies. The patterns of conservati...
BMCBI
2004
13 years 4 months ago
2004
Background: The Distributed Annotation System (DAS) allows merging of DNA sequence annotations from multiple sources and provides a single annotation view. A straightforward way t...
BMCBI
2004
13 years 4 months ago
2004
Background: The explosion in biological information creates the need for databases that are easy to develop, easy to maintain and can be easily manipulated by annotators who are m...
BMCBI
2004
13 years 4 months ago
2004
Background: The main goal in analyzing microarray data is to determine the genes that are differentially expressed across two types of tissue samples or samples obtained under two...
BMCBI
2004
13 years 4 months ago
2004
Background: Expressed Sequence Tag (EST) sequences are generally single-strand, single-pass sequences, only 200
BMCBI
2004
13 years 4 months ago
2004
Background: Many real networks can be understood as two complementary networks with two kind of nodes. This is the case of metabolic networks where the first network has chemical ...
BMCBI
2004
13 years 4 months ago
2004
Background: A central challenge in the molecular diagnosis and treatment of cancer is to define a set of molecular features that, taken together, distinguish a given cancer, or ty...