116
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WABI
15 years 6 months ago
2007 Springer
Abstract. Parameter estimation of large bio-pathway models is an important and difficult problem. To reduce the prohibitive computational cost, one approach is to decompose a large...
76
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WABI
15 years 6 months ago
2007 Springer
Graph-theoretic models have come to the forefront as some of the most powerful and practical methods for sequence assembly. Simultaneously, the computational hardness of the underl...
97
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WABI
15 years 6 months ago
2007 Springer
Predicting the secondary structure of an RNA sequence is an important problem in structural bioinformatics. The general RNA folding problem, where the sequence to be folded may con...
WABI
15 years 6 months ago
2007 Springer
When aligning biological sequences, the choice of parameter values for the alignment scoring function is critical. Small changes in gap penalties, for example, can yield radically ...
WABI
15 years 6 months ago
2007 Springer
In comparing genomic maps, it is often difficult to distinguish mapping errors and incorrectly resolved paralogies from genuine rearrangements of the genomes. A solution to this ...
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