250
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BICOB
15 years 5 months ago
2009 Springer 
We propose a two-step biclustering approach to mine co-regulation patterns of a given reference gene to discover other genes that function in a common biological process. Currently...
198
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BICOB
16 years 4 days ago
2009 Springer 
Cytoplasmic post-transcriptional modification of mRNA transcripts in the form of polyadenylated (poly(A)) tails plays a key role in their translational control. The timing and degr...
195
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BICOB
16 years 2 months ago
2009 Springer
The de novo assembly of genomes from high-throughput short reads is an active area of research. Several promising methods have been recently developed, with applicability mainly re...
208
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BICOB
16 years 2 months ago
2009 Springer 
Abstract. With the availability of hundreds and soon-to-be thousands of complete genomes, the construction of genome-scale metabolic models for these organisms has attracted much a...
219
Voted
BICOB
16 years 2 months ago
2009 Springer 
Here we present a simple method based on graph spectral properties to automatically partition multi-domain proteins into individual domains. The identification of structural domain...
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Computational Biology